T cells and B cells are normally made by the body. This causes common infections, like a cold or flu, to make the child very sick or may even lead to death. This means that the body is not able to defend itself and make the antibodies As part of the immune system, antibodies are found in the blood and help to detect and destroy invaders like bacteria and viruses. code in these genes cause the body to have little or no T cells and B cells. It is these instructions that cause certain traits, such as eye or hair color, to be inherited. Each parent passes half of their chromosomes, and thus half of their DNA instructions, onto their children. Some mutations change the protein instructions and can lead to particular health problems or disorders. A change in one or more of the DNA bases making up a gene is called a mutation. A gene is a section of DNA that holds the instructions for a specific protein. The sequence of the bases spell out instructions for making all of the proteins needed by an organism. DNA is composed of four units (called bases) that are designated A, T, G, and C. The term variants is now used in place of the term mutation., or changes to the DNA Deoxyribonucleic acid (DNA) is a molecule found in the chromosomes that carries genetic information. There are different types of variants – they can be non-problem causing (benign), disease-causing (pathogenic) or of unknown significance. Variants can happen in genes and affect how the gene functions. Variants A variant is a change or alteration in a person’s DNA sequence. Over 20 different genes are known to cause SCID. Errors in the DNA that make up a gene are called variants and can lead to diseases. Chromosomes, and the genes on those chromosomes, are passed on from parent to child. People with SCID can have a change in one or more genes A segment of DNA that contains the instructions to make a specific protein (or part of a protein). They also cannot make antibodies to protect themselves. People with SCID are not able to fight off common infections. T cells are some of the cells that may be recruited during an immune response., and
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